CRISPR Data Analysis Service

Our CRISPR data analysis service tells you exactly what your CRISPR generated data means in relation to your research question.

Without analysis, data is generally meaningless. Once you have CRISPR or CRISPR/Cas9 data, data analysis will give the raw data meaning, by translating the data into actionable information. For example, bioinformatics analysis of CRISPR data can enable the detection and annotation of Single-Nucleotide Polymorphisms (SNPs). This information can be useful for a variety of purposes such as making predictions about an individual’s risk of developing a certain disease or their susceptibility to a specific toxin.

Image shows a dna segment cut out from a larger piece and the text reads "CRISPR Data Analysis, turning Crispr data into actionable information".

CRISPR and Bioinformatics

CRISPR studies can benefit from bioinformatics expertise, no matter what stage they are at. When your end goal is generating CRISPR data that will be analysed via bioinformatics approaches, input from an expert bioinformatician helps produce robust results. Bioinformaticians can advise on everything from study design to the best analyses to reveal off-target effects.

CRISPR Data Analysis – Our Expertise

As a leading bioinformatics solutions provider, Fios Genomics can analyse various types of CRISPR-generated data, such as:

  • Gene expression and GWAS data
  • Epigenetics data
  • Microbiome data
  • Metabolomics data
  • Proteomics data

What’s more, when you choose CRISPR data analysis from Fios, we can integrate your CRISPR data with other data types, to give an overall picture of what all the data generated by your research, is telling you. We can even integrate your data with public domain data. In fact, we can provide an overview of all the available public domain data which is relevant to your research question, and provide integrated analyses with your own data to further your research and inform next steps.

Our Previous CRISPR Analysis Projects

Some of our previous CRISPR analysis projects for clients include:

  • Multivariate analysis across RNA-Seq and SNP/CNV data, alongside efficacy data from over 800 CRISPR screens
  • Identification of sensitivities to CRISPR knockouts in cell lines of interest
  • Analysing combinatorial CRISPRi screen data to investigate role of DNA Damage repair genes in cell lines

Also, you can learn more about some of our previous CRISPR projects on our client publications page.

Our CRISPR Data Analysis Service

Whether you have CRISPR data that you need analysis of, or you want to find all the public CRISPR datasets relevant to your research, we can help. So, Contact us now to tell us about your requirements. You can also view our sample bioinformatics report featuring CRISPR data, by completing the form on the  bottom of this page.

 

Request a sample CRISPR data analysis report

This report describes the integration of gene expression, copy number and mutation datasets from the Broad Avana CRISPR dataset and DepMap 21Q1 CCLE data with BRAF gene dependency data.  The aim of this report was to identify genetic features that were significantly associated with BRAF gene dependency across the DepMap cancer cell lines and indications. This approach highlighted biomarkers of BRAF dependency and could help prioritise potential novel therapeutic targets.

Fill out the form to access the report

 

Sample report request - CRISPR (CCLE)
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