Analyses for Cardiovascular and Metabolic Research
We have seen a rise in projects related to cardiovascular and metabolic diseases in recent years. We have helped researchers gain insights into diabetes, obesity, myocardial infarction, and nonalcoholic steatohepatitis (NASH).
How we can help your cardiovascular and metabolic research
By combining our expertise in bioinformatics analysis with our extensive knowledge in the cardiovascular and metabolic diseases area, we can support your research at every stage of the drug development process from pre-clinical to clinical. Our bioinformatics services can help with:
- Target and lead identification and validation
- Identifying biomarkers for measurement of drug efficacy and mechanism of action
- Predicting biomarkers for stratification/classification of patient response to drug
- Systematic analysis of metabolic disorders by combining multiple ‘omics data sources
Our bespoke solutions utilise state-of-art approaches, tailored to the data types and requirements of each project.
Selected projects we have helped with
- Understanding the molecular mechanisms following a myocardial infarction, notably the role of a gene of interest for target validation
- Differences in metabolic profiles and pathways between wild type and knock-out mice
- The evaluation of gene expression changes in response to treatment in alpha, beta, delta and ductal cells from pancreas tissue samples
- Associating biomarkers with drug induced liver injuries
For publications, visit our dedicated Publications page.
At Fios Genomics, we are completely data driven. Whatever your research area, we offer support at every stage of your research and for different purposes:
Discovery
Selecting the correct targets and/or the correct indication is essential for development success. We help support the process with robust analysis of historic or new data.
Preclinical Research
We help in experimental design and statistical analysis and guide our clients in making informed decisions during the preclinical stage.
Clinical
Research
We offer a comprehensive analysis approach for augmenting clinical trial outcomes, ensuring you get the most information out of your research.
Drug Repurposing
We have strong experience with identifying in silico new potential indications for existing drugs, reducing the cost and time of downstream wet lab validation.
